Keto Chicken and Sausage Cajun Alfredo – A Creamy, Spicy, One-Skillet Masterpiece

If you’re searching for a low-carb dinner that doesn’t skimp on flavor, this Keto Chicken and Sausage Cajun Alfredo is going to be your new weeknight favorite. Packed with bold Cajun spices, creamy Alfredo sauce, and hearty proteins, this one-skillet wonder brings Southern soul to your keto kitchen—without compromising your macros.

This recipe is perfect for those who want something rich and indulgent but still clean, grain-free, and keto-approved. It’s easy to make, deeply satisfying, and ideal for meal prepping or feeding a crowd. With layers of juicy chicken, spicy Andouille sausage, sautéed vegetables, and a silky Parmesan cream sauce, this dish is the definition of comfort with a kick.

Who This Recipe is Perfect For

This recipe is a must-try if you:

  • Follow a keto or low-carb diet and want variety that doesn’t feel restrictive.

  • Love Southern or Cajun-inspired flavors—think smoky, spicy, and savory.

  • Need a quick weeknight meal that’s rich in protein and full of flavor.

  • Are looking for a meal prep option that reheats beautifully.

  • Want a restaurant-quality dish without leaving the house (or spending a fortune).

Whether you’re cooking for yourself, your family, or meal prepping lunches for the week, this recipe delivers big results with minimal fuss.

Ingredients You’ll Need

Here’s a breakdown of what you’ll need to create this delicious Cajun Alfredo:

  • Andouille Sausage – Spicy and smoky, it adds depth and a Cajun flair.

  • Boneless Skinless Chicken Thighs – Juicy and flavorful, perfect for soaking up the seasoning.

  • Cajun Seasoning – Brings heat, boldness, and a distinctly Southern flavor.

  • Olive Oil – Used to sauté the meats.

  • Butter – Adds richness to the sauce and vegetables.

  • Onion, Celery, Red Bell Pepper – The classic Cajun trinity for flavor foundation.

  • Minced Garlic – A must for deep, aromatic flavor.

  • Heavy Whipping Cream – Forms the base of the Alfredo sauce.

  • Parmesan Cheese – Melts into the cream for a velvety, cheesy finish.

  • Cauliflower Rice – A keto-friendly rice alternative that absorbs the flavors perfectly.

  • Chopped Green Onions – A fresh garnish to brighten up the dish.

Kitchen Equipment You’ll Need

To make this recipe smooth and stress-free, gather the following kitchen tools:

  • Large nonstick or cast-iron skillet

  • Knife and cutting board

  • Wooden spoon or heat-safe spatula

  • Measuring spoons and cups

  • Cheese grater (if shredding Parmesan from a block)

  • Mixing bowl (optional, for prepping meat or vegetables)

Step-by-Step Instructions

1. Cook the Chicken

Heat olive oil in your skillet over medium-high heat. Season the chicken thighs with half of your Cajun seasoning. Add to the skillet and sauté until fully cooked—golden on the outside, juicy on the inside. Remove and set aside.

2. Brown the Sausage

Add sliced Andouille sausage to the same skillet and sauté until browned and heated through. This step adds flavor and texture. Remove and set aside with the chicken.

3. Sauté the Vegetables

Drain any excess oil from the skillet. Reduce heat to medium. Melt the butter, then add the onion, red bell pepper, and celery. Cook until softened—about 5–7 minutes. Stir in the garlic and cook for another 30 seconds until fragrant.

4. Make the Creamy Alfredo Sauce

Pour in the heavy cream and simmer, stirring occasionally, until the sauce begins to thicken. Add the Parmesan cheese and remaining Cajun seasoning. Stir until melted and combined.

5. Bring It All Together

Return the cooked chicken and sausage to the skillet. Mix in the cauliflower rice, and simmer everything together for another 5 minutes, allowing the flavors to meld and the rice to absorb the sauce.

6. Garnish and Serve

Top with chopped green onions and serve hot!

Helpful Tips for Best Results

  • Cut meat and veggies into uniform sizes for even cooking.

  • Use a good-quality Cajun seasoning or make your own to control salt and spice.

  • Don’t overcook the cream sauce—keep it at a gentle simmer to avoid curdling.

  • Fresh Parmesan melts better and gives a smoother finish than pre-grated varieties.

  • Cauliflower rice can be fresh or frozen. If frozen, thaw and squeeze out excess moisture first.

Easy Variations & Swaps

One of the great things about this recipe is its flexibility. Try these variations to customize it:

  • Make it dairy-free: Use coconut cream and nutritional yeast instead of cream and cheese.

  • Swap chicken thighs for breasts if you prefer a leaner cut.

  • Add mushrooms or spinach for extra veggies.

  • Try a different sausage: Chorizo, kielbasa, or smoked turkey sausage can also work.

  • Use zucchini noodles or shirataki noodles instead of cauliflower rice for a faux-pasta twist.

What to Serve with Cajun Alfredo

This meal is hearty on its own, but you can pair it with:

  • Keto Garlic Bread (made with almond or coconut flour)

  • Avocado slices or guacamole to cool the heat

  • A crisp side salad with lemon vinaigrette

  • Roasted asparagus or green beans

Drink Pairings:

  • A glass of dry white wine (like Sauvignon Blanc)

  • Sparkling water with lime

  • Unsweetened iced tea with lemon

  • Low-carb beer or a keto-friendly hard seltzer

How to Store and Reheat

This recipe stores and reheats incredibly well, making it perfect for meal prep.

Storing Leftovers:

  • Refrigerator: Store in an airtight container for up to 4 days.

  • Freezer: Freeze in individual portions for up to 2 months.

Reheating Tips:

  • Microwave: Reheat in 30-60 second intervals, stirring between to avoid hot spots.

  • Stovetop: Warm over medium-low heat with a splash of cream or broth to rehydrate the sauce.

Frequently Asked Questions (FAQ)

Is Cajun Alfredo keto?

Yes! This version is 100% keto. It’s high in fat and protein, and uses cauliflower rice in place of high-carb pasta or rice.

Can I use precooked chicken or sausage?

Absolutely. Just slice and heat through before adding to the sauce to ensure it’s evenly warmed and absorbs the Cajun flavors.

How spicy is this dish?

That depends on your Cajun seasoning. Some blends are spicier than others. You can adjust the amount to suit your heat tolerance—or add a pinch of cayenne for extra kick.

Can I make this vegetarian?

Yes—swap the meats for sautéed mushrooms, zucchini, or eggplant. Use veggie sausage alternatives for extra protein.

What’s the carb count per serving?

While the exact macros depend on your ingredient brands and portion sizes, each serving typically contains around 6–8 net carbs, keeping it well within keto-friendly range.

Final Thoughts

This Keto Chicken and Sausage Cajun Alfredo is proof that low-carb doesn’t mean low-flavor. With a bold Cajun kick, creamy sauce, and comforting one-skillet simplicity, it’s a recipe you’ll come back to again and again.

Whether you’re deep in keto mode or simply want a filling dinner that feels indulgent without the carb overload, this dish delivers big. It’s quick, easy, flavorful, and totally customizable.

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