If you’re searching for a family-friendly dinner recipe that’s hearty, comforting, and impossibly easy to whip up on a weeknight, look no further than this Sloppy Joe Biscuit Casserole. It’s a mouthwatering mashup of two all-American classics—Sloppy Joes and buttery biscuits—baked together into a bubbling, cheesy casserole that’s as satisfying as it is nostalgic.

This dish is tailor-made for busy households, picky eaters, and anyone craving something delicious without a long ingredient list or hours in the kitchen. With just a pound of ground beef, a can of biscuits, pantry staples, and shredded cheese, you’re only about 30 minutes away from a dinner that gets rave reviews every single time.

Why You’ll Love This Sloppy Joe Biscuit Casserole

This recipe is more than just a clever dinner idea—it’s a comfort food classic reinvented for modern home cooks. It’s the kind of meal that:

Comes together quickly with basic pantry staples
Feeds a crowd (or leaves you with fantastic leftovers)
Appeals to kids and adults alike
Can be prepped in advance and popped into the oven when needed
Easily adaptable for different dietary needs or ingredient swaps

Whether you’re cooking for a large family, hosting a casual potluck, or just need something warm and filling after a long day, this casserole hits the spot every time.

Ingredients You’ll Need

Here’s everything required to bring this dish to life:

1 lb ground beef (or ground turkey for a leaner option)
¾ cup ketchup
¼ cup water
3 teaspoons brown sugar
2 teaspoons Worcestershire sauce
2 teaspoons mustard (yellow or Dijon both work)
1 teaspoon garlic powder
1 teaspoon onion powder
¼ teaspoon salt
12 oz canned biscuits, cut into quarters
1 cup shredded cheddar cheese

These simple ingredients transform into a bold, savory filling with just the right hint of sweetness—then it’s baked under a golden biscuit crust for that crave-worthy bite.

Equipment You’ll Need

No complicated tools here—just a few kitchen basics:

Large skillet
Mixing bowl (medium or large)
Knife and cutting board (for quartering biscuits)
9×13 baking dish
Cooking spray
Spatula or spoon

How to Make Sloppy Joe Biscuit Casserole

This recipe couldn’t be easier. Here’s the step-by-step breakdown:

1. Preheat & Prep

Set your oven to 350°F and spray a 9×13 baking dish with cooking spray to prevent sticking.

2. Cook the Meat

In a large skillet over medium heat, cook the ground beef or turkey until no longer pink. Drain any excess fat to avoid a greasy casserole.

3. Make the Sloppy Joe Sauce

Stir in the ketchup, water, brown sugar, Worcestershire sauce, mustard, garlic powder, onion powder, and salt. Simmer the mixture for about 5 minutes to let the flavors meld.

4. Combine with Biscuits

Transfer the meat mixture to a mixing bowl, then add the quartered biscuit pieces. Toss everything together until the biscuits are well-coated.

5. Assemble & Bake

Pour the biscuit-meat mixture into your prepared baking dish. Spread it out evenly, then top with shredded cheddar cheese.

Bake for 28–30 minutes, or until the biscuits are golden brown and cooked through.

6. Serve and Enjoy!

Remove from the oven and let it cool for a few minutes before serving. Trust us—it’s hard to wait, but the flavor is worth it.

Tips & Tricks for the Perfect Bake

Cut the biscuits evenly so they cook at the same rate.
If the biscuits are browning too quickly, cover the top loosely with foil during the last 10 minutes of baking.
Want it extra saucy? Add 2 more tablespoons of ketchup and a splash of BBQ sauce to the mixture.
Try using honey butter biscuits for a sweet-savory twist.

Recipe Variations and Swaps

Looking to make it your own? This casserole is super flexible. Here are some easy ways to mix it up:

Protein Options

Substitute ground turkey, chicken, or plant-based ground meat for a lighter or vegetarian version.

Biscuit Alternatives

Swap canned biscuits with homemade biscuit dough, crescent rolls, or even tater tots for a fun twist.

Cheese Variations

Not a fan of cheddar? Try Monterey Jack, mozzarella, or a Tex-Mex blend for a different flavor profile.

Add Veggies

Toss in diced bell peppers, mushrooms, or corn for added texture and nutrients.

How to Store & Reheat Leftovers

This casserole is just as good the next day—if not better.

Storing

Let the casserole cool completely before storing.
Keep leftovers in an airtight container in the refrigerator for up to 4 days.

Reheating

Microwave individual portions for 1–2 minutes.
For best texture, reheat in the oven at 300°F for about 10–12 minutes.

Freezing

While biscuits can lose a bit of their texture, you can freeze leftovers.
Wrap tightly and store for up to 2 months. Reheat from frozen or thaw overnight before baking.

Suggested Pairings

This casserole is hearty on its own but plays well with plenty of sides and drinks:

Side Dishes:

Simple green salad with ranch or vinaigrette
Steamed green beans or broccoli
Corn on the cob
Sweet potato fries

Drinks:

Sweet tea, lemonade, or a cold root beer
For adults, pair with a light lager or Cabernet Sauvignon to cut through the richness

Frequently Asked Questions

Can I prep this casserole ahead of time?

Absolutely! Assemble everything (except the cheese topping), cover with foil, and refrigerate for up to 24 hours. Add cheese just before baking.

Can I use homemade biscuit dough?

Yes! Just be sure to cut it into small, even pieces and watch the bake time—it may need a few extra minutes.

Can I make it spicy?

Sure! Add crushed red pepper flakes, hot sauce, or even diced jalapeños to the meat mixture for a spicy kick.

How do I know when the biscuits are cooked through?

The top should be golden brown, and a toothpick inserted into one of the biscuit pieces should come out clean or with just a few crumbs.

Is this dish kid-friendly?

Absolutely! This is one of those recipes that picky eaters tend to devour—especially when paired with a little extra cheese on top.

Final Thoughts

Sloppy Joe Biscuit Casserole is one of those magical recipes that checks all the boxes: easy, comforting, crowd-pleasing, and budget-friendly. Whether you’re serving up a weeknight meal or feeding a hungry group, this dish is guaranteed to become a regular part of your dinner rotation.

The blend of savory meat, gooey cheese, and fluffy biscuits is a nostalgic nod to classic Americana, baked into a one-pan wonder you’ll be proud to serve.

Sloppy Joe Biscuit Casserole

Sloppy Joe Biscuit Casserole: The Ultimate Comfort Food Bake for Busy Families